Recombinant Mouse Protein IL-1B
Recombinant Mouse IL-1 Beta Protein (17.4 kDa)
IBI’s recombinant mouse IL-1 beta protein is expertly designed for research focused on inflammation and immune regulation. Produced in a Pichia pastoris (yeast) system, this protein benefits from natural folding and post-translational modifications, offering superior bioactivity compared to E. coli-derived proteins. Free from endotoxins, HIS-TAGS, and carriers, it is purified to closely resemble its native form, with a predicted molecular weight of 17.4 kDa.
Key Role of IL-1 Beta in Inflammation
Interleukin-1 beta (IL-1β) is a critical cytokine in the IL-1 family, which includes 11 proteins sharing similar structures and receptor interactions. IL-1β plays a leading role in initiating and regulating inflammatory responses, driving Th1 and Th17 immune pathways. It collaborates with other cytokines like IL-1α and IL-18 to trigger inflammation, while receptor antagonists such as IL-1ra serve to modulate these reactions by blocking receptor binding. This dynamic balance is essential for managing immune activity and inflammation.
Shipped lyophilized at room temperature without carrier protein, IBI’s recombinant mouse IL-1 beta protein can be reconstituted in sterile PBS with an appropriate carrier such as BSA or cell assay media. It is ideal for use in cell culture, as an IL-1 beta ELISA standard, or as a Western Blot control, ensuring consistent results for advanced research.
Original: $393.68
-65%$393.68
$137.79Recombinant Mouse Protein IL-1B
Recombinant Mouse IL-1 Beta Protein (17.4 kDa)
IBI’s recombinant mouse IL-1 beta protein is expertly designed for research focused on inflammation and immune regulation. Produced in a Pichia pastoris (yeast) system, this protein benefits from natural folding and post-translational modifications, offering superior bioactivity compared to E. coli-derived proteins. Free from endotoxins, HIS-TAGS, and carriers, it is purified to closely resemble its native form, with a predicted molecular weight of 17.4 kDa.
Key Role of IL-1 Beta in Inflammation
Interleukin-1 beta (IL-1β) is a critical cytokine in the IL-1 family, which includes 11 proteins sharing similar structures and receptor interactions. IL-1β plays a leading role in initiating and regulating inflammatory responses, driving Th1 and Th17 immune pathways. It collaborates with other cytokines like IL-1α and IL-18 to trigger inflammation, while receptor antagonists such as IL-1ra serve to modulate these reactions by blocking receptor binding. This dynamic balance is essential for managing immune activity and inflammation.
Shipped lyophilized at room temperature without carrier protein, IBI’s recombinant mouse IL-1 beta protein can be reconstituted in sterile PBS with an appropriate carrier such as BSA or cell assay media. It is ideal for use in cell culture, as an IL-1 beta ELISA standard, or as a Western Blot control, ensuring consistent results for advanced research.
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
Recombinant Mouse IL-1 Beta Protein (17.4 kDa)
IBI’s recombinant mouse IL-1 beta protein is expertly designed for research focused on inflammation and immune regulation. Produced in a Pichia pastoris (yeast) system, this protein benefits from natural folding and post-translational modifications, offering superior bioactivity compared to E. coli-derived proteins. Free from endotoxins, HIS-TAGS, and carriers, it is purified to closely resemble its native form, with a predicted molecular weight of 17.4 kDa.
Key Role of IL-1 Beta in Inflammation
Interleukin-1 beta (IL-1β) is a critical cytokine in the IL-1 family, which includes 11 proteins sharing similar structures and receptor interactions. IL-1β plays a leading role in initiating and regulating inflammatory responses, driving Th1 and Th17 immune pathways. It collaborates with other cytokines like IL-1α and IL-18 to trigger inflammation, while receptor antagonists such as IL-1ra serve to modulate these reactions by blocking receptor binding. This dynamic balance is essential for managing immune activity and inflammation.
Shipped lyophilized at room temperature without carrier protein, IBI’s recombinant mouse IL-1 beta protein can be reconstituted in sterile PBS with an appropriate carrier such as BSA or cell assay media. It is ideal for use in cell culture, as an IL-1 beta ELISA standard, or as a Western Blot control, ensuring consistent results for advanced research.
